Our morphological study during embryogenesis suggests that despite the different terms of small and large salivary glands formation, there is observed a stereotyped first morphogenesis stage — formation on the skin surface or in the primary oral fossa the cuticular peridermal epithelium and its ingrowth in a subordinate mesenchyme by vegetation. Ingrowth of cuticular peridermal epithelium in the primary duct forms cellular elements of excretory ducts. The formation of primary ducts is associated with proliferation of cuticular epithelium basal cells in the subordinate alcian-positive myxoid stroma, against neoangiogenesis background of which intercalated salivary glands’ ducts germs form. Thus, the first stage of salivary glands embryogenesis is characterized by a specific pattern, which induces the development of individual composition of epithelial germs.
