Examination and treatment of patients with chronic generalized periodontitis have been conducted. Application of local combined use of apigel and magnetic therapy at the complex treatment generalized periodontitis allows to reduce the rate of recurrence of periodontal disease, and to have positive influence on the indicators of free-radical oxidation and intensity of inflammation. In conclusion it is worth while determining that local combined application of apigel with magnetic therapy at the complex treatment of periodontitis is an effective method of correction of the clinical symptoms and indexes of condition of the periodont.