The effect of platelet autocryolysate on the structure of sclera and conjunctiva of intact rabbits was studied. Subconjunctival administration of platelet autocryolysate between episclera and muscle causes activation of fibroblasts, enhancement of collagen formation processes. The newly formed collagen fibers are oriented along the scleral capsule. With subconjunctival and intrascleral introduction of platelet autocryolysate along with scleral dissection, multidirectional changes in sclera, conjunctiva, and episclera were observed. At the same time, the areas of fibroblast activation and formation of collagen fibers, areas with signs of inflammation in the episclera, areas with dystrophic changes of the episclera were observed. Platelet autocryolysate under conditions of subconjunctival administration between the episclera and the muscle promotes the physiological organized formation of collagen fibers, which is accompanied by sclera-strengthening effect in rabbits under experimental conditions, and can be the basis for further investigations of the possibility of using this method in myopia treatment.
