There are discussed various pathobiological patterns of the impact of exogenic nitrites and nitrates on health. Authors argue that existing methodology of hygienic standardization doesn’t exclude the search for new approaches for establishing levels of safe inpact of exogenic factors on the organism. The modern pathophysiological concepts about disruptive impact of NO precursors contains evidence for the revision of the daily level of nitrites and nitrates with food and drinking water. Serious experimental work and pragmatic attitude should be applied for this problem.
