The analysis of contemporary data on pathogenesis of diabetic retinopathy and role played by vascular endothelial growth factor (VEGF), and pigment epithelium-derived factor (PEDF) in mechanisms of proliferation processes in retina was made. It was stressed that regulation of production and functional activity of VEGF and PEDF might be achieved via artificial irritation of brain structures (cerebellum) using different factors of physical nature. Own data on the heightening of the resistance of neural tissue to hypoxia after electrical irritation of paleocerebellar cortex are delivered.
