The work expounds the frequency of null-alleles of GSTM1, GSTT1 gene polymorphisms and NAT2 (2*4, 2*5, 2*6, 2*7) in patients suffering from pulmonary tuberculosis. The presence of GSTM1 null-allele is associated with chronicity of tuberculosis process. Percentage contribution of slow acetylators in the group of patients with pulmonary tuberculosis is significantly higher as compared with the group of healthy individuals. Rate of polymorphic variant NAT2*2*6 in the group of patients with first diagnosed pulmonary tuberculosis is significantly higher (p<0.01) as compared with healthy individuals.
