The paper presents the data of comparative research of calcium-regulated hormones, remodulation markers, as well as the state of the bone tissue in the healthy pregnant women with the pregnant women suffering from perinatal infections.
The level of calcium-regulating hormones and remodulation markers of the bone tissue were determined by chemiluminescence immunoassay. The bone tissue density was measured by ultrasound bone densitometry.
The levels of the vitamin D-hormones and osteocalcin in the pregnant women with perinatal infections was decreased compared with the healthy pregnant women, while the parathyroid hormone and the CrossLaps levels was exceed. The pregnant women of both groups were observed hypercalcuria, the pregnant women with perinatal infections had the maximal amount of calcium excretion.
Osteopenic syndrome of various degrees was detected in 81.25% of the pregnant women with perinatal infections.
Activation of the process of bone tissue remodulation in the pregnant women with perinatal infections is likely to assist in maintaining the structural and functional parameters of the bone.