The obtained data suggest the suppression of sex behavior under condition of chronic epileptic activity modeling in female rats via subthreshold doze repeated picrotoxin administration (pharmacological kindling). Administration of antioxidants — thioctic acid (alpha-lipoic acid — 30.0 vg/kg, i. p.) diminished manifestations of disturbances of sex behavior. That fact is in favor for the role played by peroxidative mechanisms in the mentioned disturbances of sex behavior.
