COMPARATIVE EFFICACY OF REPERFUSION ECG PROPERTIES AFTER ADMINISTRATION OF ALTEPLASE AND STREPTOKINASE IN PATIENTS OF DIFFERENT AGE GROUPS

The research represents historical study based on thorough biennial selection of 94 archival case records of patients with myocardial infarction with elevation of ST segment after carrying out thrombolytic therapy. The results of studying of comparative efficacy of reperfusion properties of the two most often administrated thrombolytics — alteplase and streptokinase are demonstrated in this paper. Reperfusion was estimated by its properties to elevate ST segment by 50 per cent and more from the initial point in groups of patients who were given alteplase and streptokinase, and also separately in subgroups in view of age. The results show moderately prevailing efficacy of alteplase concerning reperfusion properties in patients in more senior age groups. However, in patients under 50 years old streptokinase has demonstrated better reperfusion properties. Taking into account not such considerably prevailing efficacy of alteplase but more than 10 times as much cost, streptokinase might be considered to be the recommended thrombolytic in Ukraine.