Clinical effectiveness of “Child’s bifi-form” was investigated in children suffering from acute intestinal infections (AII). 29 children from 1 till 3.5 years old suffering from AII (gastroenteritis, gastroenterocolitis, enterocolitis, with or without toxicosis with dehydration of 1 or 2 degree) were examined. Medication “Child’s bifi-form” was prescribed with basis therapy. It was showed that including “Child’s bifi-form” in treatment of AII led to more rapid involution of the pathologic signs.