Review based on the theory of the determinant, generator and systemic mechanisms of the nervous system disturbances deals with own and other literary data concerning the functional afferents duality principle. One could read about the examples of the named principle existing and realization. Dual – pro- and antiepileptic — effects of the cerebellar foci on the epileptic activity are discussed. Duality of the functional afferents of the brain structures electrical stimulation on the generator of excitation activity is important. The mechanisms of the named functionally opposite effects of the brain structures electrical stimulation are explained on the base of the system-antisystem interrelationships principle.
