The acute bleeding today is one of the most actual problems in the practical medicine. The only method to prevent the stable increasing of haemorrhage incidence at different pathological states is improvement of early diagnosis and onset of active therapy.
The article deals with a possibility of using Willebrand factor as a main key criterion directed to determinations of volume of haemorrhage.
Experimentally it is proved a direct dependence of change of actual haemorrhage and blood deficit in organism to the change of Willebrand factor activity in case of modelling proved acure haemorrhage. A significant dependence of vascular-thrombocytar link blood coagulation on Willebrand factor.