Cholic peritonitis is a severe disease of abdominal cavity, which depends on endogenic intoxication between hardness, prognosis and percentage of mortality. In complex treatment of peritonitis, promising directions can be finding of new sanitation ways of abdominal cavity. The investigation was conducted on 180 mice of Vistar line. These animals were divided into 4 groups. Proposed complex abdominal cavity sanitation method showed its efficiency during analyzing enzymes AST and ALT: in the 4th group (with complex sanitation) numbers are close to the normal values, in comparison with 2 other groups, in which modeling of cholic peritonitis was acting too. During the research of AST more visible dynamics of the 4th group was on the 7th day. Activity of ALT in the 4th group is approximately to normal values on the 3rd day.
