EXAMINATION OF ADSORPTION ACTIVITY OF DETOXICATION AGENT “GEL SORBENT” FOR EGG ALBUMIN

Зроблено висновок, що досліджуваний засіб «Гель-сорбент» зберігає основні характеристики «Силіксу» та інших ентеросорбентів на основі нанокремнезему: високу сорбційну активність і значну швидкість адсорбції білка, водночас, він характеризується новими позитивними властивостями.

The sorption-detoxication agent “Gel sorbent” is a stabilized 5% aqueous dispersion of nano-silica, which is also made in variants with the addition of amaranth and flaxseed oil as well as of an extract of mint as biologically active components.

According to the requirements of analytical normative documentation, the pharmacological activity of such sorbents is determined by the amount of protein adsorption. The aim of the study was to determine the sorption properties of the protein (egg albumin (M = (39±4) kDa)) of the 5 samples of the remedy “Gel-sorbent”. From the obtained isotherms, the values of the limiting adsorption of protein (Amax) were calculated.

It has been concluded that the investigated “Gel-sorbent” retains the main characteristics of Silics and of other nanosilica based enterosorbents: high sorption activity and significant protein adsorption rate, but at the same time it is characterized by new positive properties.