CHARACTERISTICS OF PLASMA LIPID PROFILE IN PATIENTS WITH HYPERTENSION, COMORBID WITH GOUTY ARTHRITIS, AND ITS CORRECTION WITH ATORVASTATIN

Arterial hypertension is one of the most common risk factors for cardiovascular disease often accompanied by chronic forms of gout. This disease combination is associated with the development of hyperlipidemia, which increases cardiovascular risk even more. No current studies have been performed to check the effect of medium doses of atorvastatin in such comorbid pathology. 22 male patients with gout and arterial hypertension had lipid profile checked before and after 42 days of standard treatment additionally including 20 mg of atorvastatin daily.

It was found that initial LDL cholesterol was elevated in 91% of studied subjects. After the treatment significant lowering of total cholesterol by 24.96%, LDL cholesterol by 27.21%, VLDL cholesterol by 21.82%, triglyceride levels by 24.69% was discovered. HDL cholesterol and atherogenic index showed insignificant decrease.