In acute experiments on Wistar rats it was shown that corazol kindling is followed by the decreasing of those indices which were determined in “open field” test. Namely, the number of crossed squares as well as the number of rearings were substantially reduced. Ketogenic diet (KD) (80.0% of lipids, 3.3% of carbohydrates and 16.7% of proteins), which was applied for 2 and 4 weeks induced protective action with regard to kindling-induced effects upon animal’s behavior, which was blocked by naloxon (1.0 and 10.0 mg/kg, i. p.). The enlargement of opiate-induced components of posture-tonic reactions-explosivness, exophthalmos, adduction of extremities, decreasing of pain-induced reactions, increasing of tail tonus, loosing of the ability to hold on the rode and grasping of the pencil were seen in kindled rats. Mentioned behavioral reactions were blocked by KD and this effect of KD was blocked by naloxon (10.0 mg/kg, i. p.).
