COMPARATIVE ANALYSIS OF BARIUM SULFATE AND TALC IN STRENGTH OF ADHESIVE PROCESS IN FEMALE RATS

Approbation of experimental models of adhesions’ forming in rats showed their availability by mean of intra-peritoneal introduction of barium sulfate or talc to study co-operative interprocess of inflammation, angiogenesis and fibrous degeneration in pathogenesis of postsurgical adhesions in women. It is settled that talc administration causes the acceleration of signs, typical for pathogenesis of adhesions: amplification of inflammation, angiogenesis and fibrous degeneration. The data suggest that the experimental model of talc-induced adhesive process may be recommended for further use as a basal experimental model for studying pathogenesis of postsurgical adhesions for women.