The inhibition of active avoidance, which was induced be maximal electroshock seizures, have been successfully blocked by derivative of peptideamidobenzophenones (PABPh) and diazepam. Maximally developed protective effect of derivative of PABPh was characterized by the net increasing of the number of successfully avoided electric irritations by 59.4% when compared with the similar index in the group treated with diazepam. At the same time it remained to be less by 39.3% when compared with the corresponded index measured in intact rats. ED50 of diazepam, which protected active avoidance in 50% of intact rats was 3.12 times less in comparison with the similar dosage, which was determined for derivative of PABPh. Combined usage of drugs revealed additive character of action.
