• On metabolic deteriorations in pentylenetetrazol (PTZ) kindled rats revealed with glucose tolerance test and liver histology 

  Pastukhov, O. O.; Pervak, M. P.; Smirnov, I. V.; Bukreeva, N. I.; Litvinenko, M. V.; Godlevsky, L. S. (2024)

  Manifestations of metabolic syndrome (MS) man‑ ifestations in chronic epilepsy models were in the scope of the investigation. Kindling was induced by daily injections of PTZ at a dose of 35 mg/kg i.p. for three weeks. ...
• Cerebellar transcranial direct current stimulation (tDCS) and pitolisant prevented behavioral and neuroinflammatory disturbances in pentylenetetrazol (PTZ) kidnling 

  Pervak, M. P.; Yehorenko, O. S.; Onuphrienko, O. V.; Varava, S. V.; Litvinenko, M. V.; Godlevsky, L. S. (2024)

  The work aimed to investigate behavioral mani‑festations in PTZ‑kindled rats under combined treat‑ment with the histamine H3 receptor inverse agonist pitolisant and mTOR blocker rapamycin. Kindling was produced in Wistar ...
• Applying bioactive compounds of Pseudomonas SPP. For medicine substance development 

  Marchenko, M.; Rusakova, M. (2024)

  Infectious diseases are still a worldwide important problem. This fact has led to the characterization of new biomarkers that would allow an early, fast and reliable diagnostic and targeted therapy. In this context, ...
• Сomplexes of Nd(III) and 3d-metals based on ethylenediaminedisuccinic acid as potential antifungal agents 

  Trunova, O. K.; Rusakova, M. Yu.; Berezhnytska, O. S.; Rohovtsov, O. O.; Makotryk, T. O.; Трунова, О. К.; Русакова, М. Ю.; Бережницька, О. С.; Роговцов, О. О.; Макорик, Т. О. (2023)

  Neodymium heterometallic complexes [(NdМIIEDDS)(H2O)6]∙n2H2O (МII=Zn, Co; n = 3; 2) were synthesized by the «block» synthesis method using protonated ethylenediaminedisuccinate of the 3-d metal and NdIII nitrate. The ...
• Lower rim-modified calix[4]arenes with fragments of EDTA (DTPA) and their Ln(III) complexes (Ln = Yb, Lu): synthesis and NIR-luminescent properties 

  Smola, S. S.; Fadieiev, Ye. N.; Rusakova, M. Yu.; Snurnikova, O. V.; Alyeksyeyeva, O. A.; Rusakova, N. V.; Смола, С. С.; Фадєєв, Є. М.; Русакова, М. Ю.; Снурнікова, О. В.; Алексеєва, O. A.; Русакова, Н. В. (2020)

  Derivatives of p-tert-butylcalix[4]arene substituted on the lower rim with fragments of aminopolycarboxylic acids (EDTA, DTPA) were obtained. Mono and binuclear complexes with lanthanide (III) ions were synthesized using ...
• Homo- and heteronuclear Yb(III) and Lu(III) complexes with calix[4]arene modified with porphyrin substituents 

  Rusakova, N. V.; Snurnikova, O. V.; Smola, S. S.; Korovin, O. Yu.; Malinka, E. V.; Rusakova, M. Yu.; Русакова, Н. В.; Снурнікова, О. В.; Смола, С. С.; Коровін, О. Ю.; Малінка, О. В.; Русакова, М. Ю. (2023)

  In this work we describe the approaches for the synthesis of lanthanide-containing homo- and heteronuclear complexes using 5,11,17,23-tetra-tert-butyl-25,27-dihydroxy-26,28-bis[(N-meso- (p-aminophenyl)-meso-triphenylpo ...
• Role of intensity of electrical stimulation (ES) in the cerebellar antiepileptic effectiveness under conditions of diazepam administration 

  Godlevsky, L.; Pervak, M.; Poshyvak, O. (2021)

  ES of brain structures combined with antiepileptic drugs is a promising approach for better pharmacological control of resistant seizures. Aims. To investigate the dynamic of penicillin-induced foci in cats' brain cortex ...
• Role of peroxisomal proliferator-activated Y-receptors in analgesia induced with cerebellar stimulations in kindled rats 

  Pervak, М.; Poshyvak, O.; Son, H.; Prybolovets, K.; Latypov, K.; Godlevsky, L. (2021)

  Background. Antiepileptic effects induced with cerebellar transcranial direct current stimulation (TDCS), and the role of peroxisomal proliferator-activated γ-receptors (PPARγ) in its development have been shown (Godlevsky, ...
• Pioglitazone intensifies antiseizure effects of cerebellar transcranial direct current stimulation (TDCS) upon kindled seizures 

  Pervak, M.; Godlevsky, L.; Poshyvak, O.; Latypov, K.; Prybolovets, K. (2021)

  Background and aims The suppression of epileptic activity follows TDCS. It was shown that blocking peroxisomal proliferator-activated γ-receptors (PPARγ) with BADGE, (100 mg/kg, i.p.) prevented antiseizure effects caused ...
• Neurodegeneration and neoangiogenesis in the cerebellar cortex in pentylenetetrazol (PTZ) - kindled rats treated with axitinib and rapamycin 

  Godlevsky, L.; Pervak, M.; Poshyvak, O.; Latypov, K.; Prybolovets, K. (2021)

  Morphological changes induced in pentylenetetrazol (PTZ)- kindled rats create the basis for the resistance of chronic brain epileptization. Cerebellar contribution to kindling seizures development was shown (Godlevsky ...
• Neuronal loss and angiogenesis are suppressed with cerebellar transcranial direct current stimulation in pentyelenetetrazol kindled brain 

  Pervak, M.; Bidnyuk, V. K.; Varava, S. V.; Al-Nadawi, N.; Latypov, K. A.; Godlevsky, L. S. (2023)

  Loss of neurons and angiogenesis underlay pathogenesis of chronic epilepsy. The aim of the work was to investigate the neuronal and microvascular density of the frontal cortex, ventral hippocampus, and retina of ...
• Daytime sleep-wakefulness cycle disturbances are effectively reversed with pitolisant in pentylenetetrazol-kindled rats 

  Yehorenko, O. S.; Pervak, M.; Latypov, K. A.; Prybolovets, K.; Shcheglov, I. A.; Godlevsky, L. S. (2023)

  Chronic brain eptisation induces sleep-wakefulness (SW) disturbances. The work aimed to investigate SW cycle in pentylenetetrazole (PTZ)- kindled rats under combined treatment with the histamine H₃ inverse agonist ...
• Synergy of antiseizure and anxiolytic action of rapamycin and histamine H₃ inverse agonist pitolisant on the PTZ-kindled seizures 

  Poshyvak, O. B.; Pinyazhko, O. R.; Pervak, M.; Yehorenko, O. S.; Prybolovets, K.; Godlevsky, L. S. (2023)

  Neuroinflammatory contribution is principal for developing chronic epileptic seizures. The work aimed to investigate chronic seizures and anxious behavior in pentylenetetrazole (PTZ)-kindled rats under combined treatment ...
• Peculiarities of the organs of the reproductive system of women of reproductive age with liver dysfunction under the influence of exogenous pollutants 

  Lobashova, O. I.; Nasibullin, B. A.; Baiazitov, D. M.; Kashchenko, O. A.; Koshelnyk, O. L.; Tregub, T. V.; Kovalchuk, L. Y.; Chekhovska, G. S.; Kachailo, I. A.; Gargin, V. V. (2023)

  The widespread use of chemicals by modern society and the prevalence of harmful habits (alcoholism, tobacco smoking, drug addiction) leads to an unnaturally high intake of exogenous pollutants in the human body, which can ...
• Functional links in the brain cortex of kindled rats evaluated at different stages of kindling seizures precipitation 

  Pervak, M. P.; Godlevsky, L. S. (2023)

  The work investigated the relationships between brain structures established in different periods of pentylenetetrazol (PTZ)-induced kindled seizure precipitation. As structures for investigations, the cortical ones of ...
• COVID-19-Related Age Profiles for SARS-CoV-2 Variants in England and Wales and States of the USA (2020 to 2022): Impact on All-Cause Mortality 

  Jones, Rodney P.; Ponomarenko, A. (2023)

  Since 2020, COVID-19 has caused serious mortality around the world. Given the ambiguity in establishing COVID-19 as the direct cause of death, we first investigate the effects of age and sex on all-cause mortality during ...
• Cerebellar contribution to absence epilepsy 

  Godlevsky, L. S.; Pinyazhko, O. R.; Poshyvak, O. B. (2020)

  The new aggregate data analyses revealed the earlier missing role played by the cerebellum long-term electrical stimulation in the absence epilepsy. Neurophysiologic data gained by authors favor that cerebellar serial deep ...
• Editorial: Ion-channels in epilepsy 

  Akyuz, E.; Lazarowski, A.; Cabo, C.; Godlevsky, L. S.; Shaikh, Mohd. F.; Doganyigit, Z. (2023)

  The research title “Ion-channels in epilepsy” that we have prepared has accepted articles from important researchers in the field from countries such as the United States of America, Australia, Germany, China, and Spain. ...
• Sol-gel processed SiO2-AL2O3 xerogels: synthesis and luminescent properties 

  Smola, S. S.; Fadieiev, Ye. N.; Rusakova, M. Yu.; Efryushina, N. P.; Rusakova, N. V.; Смола, С. С.; Фадєєв, Є. М.; Русакова, М. Ю.; Єфрюшина, Н. П.; Русакова, Н. В. (2020)

  SiO 2-Al2O3 xerogels with various Si : Al ratios were synthesized via sol-gel method (two kinds of synthetic procedures were used) and characterized by means of elemental analysis, XRD, thermogravimetry and IR spectroscopy. ...
• Tests for self-preparation for the integrated test control on the physiology for students of the general medicine specialty of the ii-nd grate 

  Onufrienko, O. V.; Topal, M. M.; Lyashenko, S. L.; Pryshchepa, O. O.; Denysenko, O. V.; Volokhova, G. O.; Kaschenko, O. A. (2019)

  Proposed educational and methodological tests contain test tasks on the subject “Physiology”. Present educational and methodical tests are designed for students of the 2-nd grade of the Medical faculty studying Physiology.

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