Male Wistar rats have been treated with ketogenic diet (KD) during four weeks. The increase of non-protein thiol groups both in hemispheres and cerebellum (by 5.1 and 5.3 times correspondently) have been noted. Thiol protein groups raised in cerebellum as well by 1.32 times when compared to intact rats (control). KD induced decrease of tumor necrozing factor alpha in cerebellum by 2.2 times as well as the decrease of thiobarbituric acid reactive products (TBARP) in hemispheres and cerebellum by 2.0 and 1.47 times. TBARP level was reduced in brain of kindled rats by 65.3%, while disulfide groups were reduced by 53.3% with KD diet. At the same time the level of protein thiol groups raised by 49.4%.
