Abstract:
Background and aims
The suppression of epileptic activity follows TDCS. It was shown
that blocking peroxisomal proliferator-activated γ-receptors
(PPARγ) with BADGE, (100 mg/kg, i.p.) prevented antiseizure effects
caused with cerebellar TDCS (Godlevsky L.S., Pervak M.P., 2019).
Aim. To investigate effects of cerebellar TDCS under conditions of
treatment with the agonist of PPARγ pioglitazone upon
pentylenetetrazol (PTZ) - kindled seizures.