Abstract:
Herpes simplex keratitis (HSK) is a severe ophthalmic pathology which comprises
20-50% of inflammatory diseases in the cornea. Since keratitis is characterized
by a long-term duration, severity, and a tendency to recurrence, studies on
ophthalmic herpes and searches for new treatments are of great relevance.
Our clinical case demonstrated successful combined treatment of a recurrent stromal
herpetic corneal lesion with ulceration. Both treatments, conservative (complex
etiotropic, anti-viral, anti-inflammatory, and nutrition-improving) and surgical (an onlay
technique), were successful. At 12 months after surgery, the patients had no pain syndrome;
the corneal surface was epithelialized. No recurrence of herpetic keratitis was observed.
Thus, a combination of etiotropic pathogenic treatment and AM transplantation
appears to be effective for severe long-lasting recurrent herpetic keratitis with the
presence of defects on the corneal surface.
